Fortune Magazine has released its inaugural Crypto 100 rankings, marking a milestone in the mainstream financial industry's recognition of digital assets. The list evaluates over 3,000 companies across ten categories, from ETFs and TradFi to DeFi and mining, in collaboration with blockchain analytics firm Inca Digital and input from more than 200 crypto experts. The rankings reflect how traditional finance giants are now central players in the crypto ecosystem.

BlackRock claimed the top spot in the Digital Asset Tokens and ETFs category, driven by the rapid success of its spot Bitcoin and Ethereum ETFs, which have funneled billions in institutional capital into crypto since their 2024 and 2026 launches. Franklin Templeton led the TradFi category, recognized for its aggressive move into tokenized funds and on-chain settlement. Coinbase ranked first in centralized finance (CeFi), ahead of Binance, while Robinhood took the fintechs category.

In a notable shift, Hyperliquid, a decentralized perpetuals exchange built on its own Layer 1 blockchain, topped the DeFi category. Its rise followed the May 2026 launch of HYPE token ETFs—the first regulated investment products tied to a DeFi-native token—drawing early inflows of $75M to $160M. Other category leaders include Andreessen Horowitz in venture capital, Tether in stablecoins, Chainalysis in crypto services, and MARA in mining. Fortune also released a companion Crypto Innovators 30 list.